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Symbol Name ID |
Smad7
SMAD family member 7 MGI:1100518 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased B cell apoptosis |
decreased B cell proliferation |
decreased T cell proliferation |
abnormal thymus morphology |
thymus hypoplasia |
abnormal class switch recombination |
abnormal T-helper 1 cell differentiation |
decreased activated T cell number |
decreased interferon-gamma secretion |
increased interferon-gamma secretion |
decreased interleukin-10 secretion |
decreased interleukin-17 secretion |
decreased interleukin-9 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
increased susceptibility to experimental autoimmune encephalomyelitis |
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| Availability | Mouse Genotype | ||||||||||||||||
| Smad7Gt(YHC053)Byg/Smad7Gt(YHC053)Byg | |||||||||||||||||
| Smad7tm1Rheu/Smad7tm1Rheu | |||||||||||||||||
| Tg(Cd2-Smad7)#Chbe/0 | |||||||||||||||||
| Smad7tm1.1Ink/Smad7tm1.1Ink Tg(Cd4-cre)1Cwi/0 (conditional) |
* | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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